The facility will be known as the "The Pauline and Stanley Foster Hospital for Cancer Care," and is slated to open in two years. It will occupy three floors of the medical center, with more than 100 beds.
Foster's husband died of a form of multiple myeloma 13 years ago.
"There was really no center to go to," she said. "You tried your luck, and unfortunately his luck didn't hold out."
Stanley Foster was responsible for turning Hang Ten into an iconic clothing line.
"I also lost my brother to cancer, and at the time, he needed to be in a hospital, but there weren't any beds," his widow said. "So after witnessing that, I felt that the best thing I could do would be to make sure that other people had beds and had the opportunity to have the kind of care that would help, and hopefully cure them."
Pauline and Stanley Foster previously provided financial support for the Shiley Eye Center, the Rady School of Management and a Masters of Business Administration fellowship fund.