Royal had scoring catches of 47 and 43 yards, his second straight two-touchdown game. The Chargers (3-1) extended their winning streak to three.
Passing because the Chargers' running game is nonexistent due to injuries to Ryan Mathews and Danny Woodhead, Rivers had his second three-touchdown game of the season. He went 29 of 39.
Royal had five catches for 105 yards. Keenan Allen had 10 for 135, both career highs, and Malcom Floyd had a 24-yard touchdown catch.
Bortles made his first start for the Jaguars (0-4), threw one touchdown pass, was intercepted twice and twice had Jacksonville in the lead in the first half.
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