UCSD professor discusses $9M grant for diabetes research

SAN DIEGO (KUSI) – UC San Diego received roughly $9 million in grants for a pair of research projects that will attempt to identify the cellular actions that lead to the development of Type 1 diabetes.

The National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, awarded grants of $3.8 million and $5.1 million to the projects that will study pancreatic beta cells, which
produce insulin and lead to the development of diabetes when damaged.

A research team led by Dr. Maike Sander and Kyle Gaulton, two professors in the UCSD School of Medicine’s Department of Pediatrics, will use the $3.8 million grant to analyze the genes associated with elevated genetic
risk for type 1 diabetes and beta cell functions by using a “reference map” of pancreatic cells.

The research team will then use CRISPR gene editing to determine which genes lead to cell survival or death and test that information on a pancreatic organoid, which is being developed with the $5.1 million grant from
stem cells from people with type 1 diabetes.

Dr. Maike Sander, a professor at UC San Diego School of Medicine, came to KUSI to discuss the projects.

Categories: Local San Diego News